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High salt diet-induced proximal tubular phenotypic changes and sodium-glucose cotransporter-2 expression are coordinated by cold shock Y-box binding protein-1
Friday, September 24th, 2021
Anja Bernhardt, Saskia Häberer, JingJing Xu, Hannah Damerau, Johannes Steffen, Charlotte Reichardt, Katharina Wolters, Hannes Steffen, Berend Isermann, Katrin Borucki, Nadine Artelt, Nicole Endlich, Renata
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Thursday, July 29th, 2021
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium Handling in Sprague Dawley Male Rats
Tuesday, May 25th, 2021
Irin Parvin, Madeline Gauthier, Melissa Dennis, Christopher Banek, “Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium
Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt Hypertensive Rats
Tuesday, May 25th, 2021
Madeline Gauthier, Melissa Rafet Dennis, Irin Parvin, Kyle Schwartz, Christopher Banek, “Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt
Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular Filtration Responses in Aging PT-Agtr1a-/- Mice
Tuesday, May 25th, 2021
Xiao Li, Rumana Hassan, Jia Zhuo, “Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular
Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction
Sunday, May 2nd, 2021
Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinweichi Nwosisi, Ming-Zhi Zhang, and Raymond C. Harris, “Activation
Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury
Tuesday, April 27th, 2021
Nirupama Ramkumar, Deborah Stuart, Caitlin S Peterson, Chunyan Hu, William Wheatley, Jae-Min Cho, J David Symons, and Donald E Kohan, “Loss of Soluble (Pro)renin Receptor
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition
Thursday, April 1st, 2021
Danielle E. Soranno, Lara Kirkbride-Romeo, Sara A. Wennersten, Kathy Ding, Maria A. Cavasin, Peter Baker, Christopher Altmann, Rushita A. Bagchi, Korey R. Haefner, Christian Steinkühler,
A dose-escalating toxicology study of the candidate biologic ELP-VEGF
Wednesday, March 24th, 2021
Jamarius P Waller, Stephen P Burke, Jason Engel, Alejandro R Chade, Gene L Bidwell 3rd, “A dose-escalating toxicology study of the candidate biologic ELP-VEGF”, Scientifc
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT- Agtr1a-/- Mice
Tuesday, March 9th, 2021
Xiao Chun Li, Ana Paula Oliveira Leite, Xiaowen Zheng, Chunling Zhao, Xu Chen, Liang Zhang, Xinchun Zhou, Isabelle Rubera, Michel Tauc, Jia Long Zhuo, “Proximal
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
Monday, January 25th, 2021
Stefan Rudloff, Mathilde Janot, Stephane Rodriguez1, Kevin Dessalle, Willi Jahnen-Dechent, & Uyen Huynh-Do, “Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress,”
No Evidence for Brain Renin-Angiotensin System Activation During DOCA-Salt Hypertension
Wednesday, January 13th, 2021
Estrellita Uij, Liwei Ren, Katrina M. Mirabito Colafella, Richard van Veghel1, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Jae B. Kim, Stephen Huang,
Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice
Thursday, October 29th, 2020
Sarah Faubel, “Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: PO0147 2020.
Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal Blood Pressure And Attenuates Angiotensin Ii-induced Hypertension By Increasing Glomerular Filtration And The Pressure-natriuresis Response
Monday, September 21st, 2020
Xiao C Li, Ana P Leite, Liang Zhang, Jia L Zhuo, “Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal
Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease
Monday, September 21st, 2020
Dominique M Bovee, Liwei Ren, Don Foster, A.H. J Danser, “Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease,” American Heart
Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy
Monday, September 21st, 2020
Satoshi Shimada, Allen W Cowley, “Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy,” American Heart Association Journals – Hypertension, September 9, 2020,
Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats with a prolonged high fat diet from an early age
Monday, July 13th, 2020
Lidia Oltra, Virginia Reverte, Antonio Tapia, Juan M. Moreno, Francisco J. Salazar, Maria T. Llinas, “Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats
Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity
Wednesday, June 24th, 2020
Bochra Tourki, Vasundhara Kain, Saame Raza Shaikh, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade, “Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and
Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After Unilateral Ischemic Injury
Wednesday, June 10th, 2020
Lies Moonen, Cristina Cuesta-Apausa, Francisco J. Lopez-Hernandez, Carlos Martinez Salgado, Patrick D’Haese, Benjamin Vervaet, “Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After
Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct
Wednesday, June 10th, 2020
Chongxu Shi, “Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct,” ERA-EDTA Meeting 2020, Nephrology Dialysis Transplantation 35 (Supplement 3):P0513.
Renomedullary Interstitial Cell Endothelin A Receptors Regulate BP and Renal Function
Monday, June 8th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Georgina Gyarmati, Chuan-Ming Hao, Peter Hansell and Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulate
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism
Wednesday, May 27th, 2020
Chongxu Shi, Tehyung Kim, Stefanie Steiger, Shrikant R. Mulay, Barbara M. Klinkhammer, Tobias Bäuerle, Maria Elena Melica4,5, Paola Romagnani, Diana Möckel, Maike Baues, Elmina Mammadova-Bach,
Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function
Wednesday, May 27th, 2020
Camila Kochi, Indira Pokkunuri, Ankita Salvi, Mohammad Asghar, Samina Salim, “Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function,” Journal Clinical and Experimental
Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function
Friday, April 24th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function,” Federation of
Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion Injury in Rats
Friday, April 24th, 2020
Zhengrong Guan, Wenguang Feng, Colton E. Remedies, Bailey A. McEachen, Paul W. Sanders, Edward W. Inscho, “Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion
Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction Independent of Cystogenesis
Wednesday, April 22nd, 2020
Jayalakshmi Lakshmipathi, Yang Gao, Chunyan Hu, Deborah Stuart, Jonathan Genzen, Nirupama Ramkumar and Donald E. Kohan, “Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction
Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia
Wednesday, April 8th, 2020
Shungang Zhang, MS; Joshua D. Breidenbach, MS; Fatimah K. Khalaf, MBCHB; Prabhatchandra R. Dube, PhD; Chrysan J. Mohammed, BA; Apurva Lad, MS; Stanislaw Stepkowski, PhD;
Targeted Inhibition of Gut Microbial TMAO Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
Wednesday, April 8th, 2020
Nilaksh Gupta, Jennifer A. Buffa, Adam B. Roberts, Naseer Sangwan, Sarah M. Skye, Lin Li, Karen J. Ho, John Varga, Joseph A. DiDonato, W.H. Wilson
α2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease
Wednesday, February 26th, 2020
Lydia Hering, Masudur Rahman, Henning Hoch, Lajos Markó, Guang Yang, Annika Reil, Mina Yakoub, Vikram Gupta, Sebastian A. Potthoff, Oliver Vonend, Donna L. Ralph, Susan
Murine models of renal ischaemia reperfusion injury: An opportunity for refinement using non-invasive monitoring methods
Friday, December 27th, 2019
Rachel Harwood, Joshua Bridge, Lorenzo Ressel, Lauren Scarfe, Jack Sharkey, Gabriella Czanner, Marta Garcia-Fiñana, Philip Kalra, Aghogho Odudu, Simon Kenny, Bettina Wilm, Patricia Murray, “Murine
Proximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice
Thursday, December 19th, 2019
Xiao C. Li, Dongmin Zhu, Xu Chen, Xiaowen Zheng, Chunling Zhao, Jianfeng Zhang, Manoocher Soleimani, Isabelle Rubera, Michel Tauc, Xinchun Zhou, Jia L. Zhuo, “Proximal
Prenatal Sildenafil Therapy Improves Cardiovascular Function in Fetal Growth Restricted Offspring of Dahl Salt-Sensitive Rats
Tuesday, December 17th, 2019
Fieke Terstappen, Frank T. Spradley, Bhavisha A. Bakrania, Sinéad M. Clarke, Jaap A. Joles, Nina D. Paauw, Michael R. Garrett, A. Titia Lely, Jennifer M.
Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen
Sunday, December 8th, 2019
Estrellita Uij , Katrina M. Mirabito Colafella , Yuan Sun , Liwei Ren , Richard van Veghel , Ingrid M. Garrelds l, René de Vries
AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats
Wednesday, November 27th, 2019
Cunningham MW Jr, Castillo J, Ibrahim T, Cornelius DC, Campbell N, Amaral L, Vaka VR, Usry N, Williams JM, LaMarca B, “ AT1-AA (Angiotensin II
The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk
Thursday, November 21st, 2019
Eva-Maria Pastor-Arroyo, Nicole Gehring, Christiane Krudewig, Sarah Costantino, Carla Bettoni, Thomas Knöpfel, Sibylle Sabrautzki, Bettina Lorenz-Depiereux, Johanne Pastor, Tim M. Strom, Martin Hrabě de Angelis,
Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a Robust and Durable Antihypertensive Effect
Sunday, November 10th, 2019
Estrellita Uijl, Katrina M. Mirabito Colafella, Ewout J. Hoorn, Jae B. Kim, Donald J. Foster, Alexander H. Danser, “Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a
Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation
Wednesday, October 30th, 2019
Gregory J. Weber, Jaleyea Foster, Sathnur B. Pushpakumar, Utpal Sen, “Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized
Combined AT2 Receptor Stimulation AT1 Receptor Blockade Does Not Cause Renal Dysfunction
Monday, October 21st, 2019
Dhaniel Baraldi, Lucinda M Hilliard, Tracey A Gaspari, Kate M Denton, Robert E Widdop, “Combined AT2 Receptor Stimulation AT1 Receptor Blockade Does Not Cause Renal
Exposure to placental ischemia impairs postpartum maternal renal and cardiac function in rats
Thursday, October 17th, 2019
Nina D. Paauw, Jaap A Joles, Frank T. Spradley, Bhavisha Bakrania, Zsuzsanna K Zellenger, Arie Franx, Marianne C. Verhaar, Joey P. Granger, A. Titia Lely,
Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and Cardiopulmonary Resuscitation (CA/CPR) in Mice
Sunday, October 6th, 2019
Michael Hutchens, Rumie Wakasaki, Ian P. Coe,Mohammed Z. Ferdaus, James A. McCormick, Sharon Anderson, “Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and
Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats
Wednesday, September 25th, 2019
Hilliard LM, Colafella KM, Bulmer LL, Puelles VG, Singh RR, Ow CP, Gaspari T, Drummond GR, Evans RG, Vinh A, Denton KM, “Chronic recurrent dehydration
Intrarenal ACE as a Catalyst for Hypertension
Friday, September 20th, 2019
Gonzales-Villaobos R.A., “Intrarenal ACE as a Catalyst for Hypertension,” J. Am. Soc. Nephrol. Kidney Week 2016.
Intrauterine Growth Restriction Programs a Greater Age-related Decline in Renal Function Associated With Increased Susceptibility to Chronic Renal Injury
Thursday, September 12th, 2019
Ashley D Newsome, Gwendolyn K Davis, Norma B Ojeda, Barbara T Alexander, “ Intrauterine Growth Restriction Programs a Greater Age-related Decline in Renal Function Associated
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice
Monday, September 9th, 2019
SR Mulay, Eberhard JN, Pfann V. et al,“Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice,” Am J Physiol Renal Physiol;
Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension
Saturday, September 7th, 2019
Spradley FT, Tan AY, Joo WS, Daniels G, Kussie P, Karumanchi SA, Granger JP.,“Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension,” Hypertension. 2016 Apr;67(4):740-7. doi:
Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure
Thursday, August 22nd, 2019
Kittikulsuth W, Stuart D, Van Hoek A.V., Kohan D.E., “Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water
Mutation of the Nicotinamide Adenine Dinucleotide Phosphate-Oxidase Subunit p67phox Protects the Dahl-S Rat From Salt-Induced Reductions in Medullary Blood Flow and Glomerular Filtration Rate
Sunday, August 18th, 2019
C. Evans LC, Ryan RP, Broadway E, Skelton MM, Kurth T, Cowley AW. Null, “Mutation of the Nicotinamide Adenine Dinucleotide Phosphate-Oxidase Subunit p67phox Protects the
Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Convertin Enzyme
Friday, August 16th, 2019
Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA, “Salt Sensitivity in Response to Renal Injury
Renal Angiotensin-Converting Enzyme Is Essential for the Hypertension Induced by Nitric Oxide Synthesis Inhibition
Sunday, August 4th, 2019
Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WB, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos
Renal generation of angiotensin II and the pathogenesis of hypertension
Saturday, August 3rd, 2019
C. Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA, “Renal generation of angiotensin II and
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression
Tuesday, July 30th, 2019
Trudu M, Janas S, Lanzani C, Debaix H, Schaeffer C, Ikehata M, Citterio L, Demaretz S, Trevisani F, Ristagno G, Glaudemans B, Laghmani K, Dell’Antonio
Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats
Monday, July 29th, 2019
Cowley AW, Ryan RP, Kurth T, Skelton MM, Schock-Kusch D, Gretz N, “Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats,”

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